If you’re in the market for a lash serum, you probably noticed that some of them contain prostaglandins while others don’t. Prostaglandins serums are effective but can cause some side effects, some of which are permanent.
Thankfully, peptides-based serums are an excellent alternative with less chance for side effects.
In this article, I compiled a list of popular eyelash growth serums and analyzed the ingredients to know if they contained prostaglandins or not. That way, you can choose the product that’s right for you!
Let’s dive into it!
Disclaimer: Although I have been doing lash enhancement treatments for years, I am not a doctor. All content and information in this post are for informational and educational purposes only and do not constitute medical advice. Always seek the advice of your own Medical Provider regarding any questions or concerns you have about your specific health before implementing any recommendations or suggestions from our Website.
Why It Matters
Latisse is the only FDA-approved eyelash growth serum on the market. The active ingredient is bimatoprost, a type of prostaglandin.
Now, because of the extensive clinical studies that were done, we know that Latisse is effective at growing your eyelashes, but we also know that it comes with possible side effects.
Therefore, any other eyelash serum that uses a prostaglandin analog compound is subject to the same side effects.
The most common adverse events from prostaglandin lash serums are:
- Itchy eyes
- Darkening of the skin around the eye
- Darkening of the eye color
- Eye Inflammation
- Swelling of the retina
- Fat atrophy around the eye
So what’s the problem?
Except for Latisse, prostaglandin-based lash growth serums are sold as cosmetics and are not subject to FDA approval like a medication would.
This means that the companies don’t have to do extensive safety testing like they would for a drug.
That’s a big issue.
In reality, these products should be treated as a medication since they use an active ingredient.
That’s why deciding whether or not you are okay with the potential side effects of a prostaglandin analog eyelash growth serum is so important.
Lash Serums With Prostaglandins
|Eyelash Serum||Contains Prostaglandin?||Active Ingredient||Ingredient List|
|Latisse||Yes||Bimatoprost||Active ingredient: bimatoprost|
Inactive ingredients: benzalkonium chloride; sodium chloride; sodium phosphate, dibasic; citric acid; and purified water. Sodium hydroxide and/or hydrochloric acid may be added to adjust pH. The pH during its shelf life ranges from 6.8 – 7.8.
|GrandeLASH||Yes||Isopropyl Cloprostenate||Water/Aqua/Eau, Panthenol, Glycerin, Sodium Citrate, Leuconostoc/Radish Root Ferment Filtrate, Alanine, Alcohol, Aloe Barbadensis Leaf Juice, Arctostaphylos Uva URSI Leaf Extract, Arginine, Aspartic Acid, Calcium Gluconate, Caprylyl Glycol, Chamomilla Recutita (Metricaria) Flower Extract, Ethylhexylglycerin, Gluconolactone, Glycine, Hexylene Glycol, Histidine, Honey Extract/Mel/Extrait de Miel, Hydrolyzed Glycosaminoglycans, Hydrolyzed Yeast Extract, Hydroxyethylcellulose, Isoleucine, Isopropyl Cloprostenate, Magnesium Ascorbyl Phosphate, Panax Ginseng Root Extract, PCA, Phenylalanine, Polysorbate 20, Proline, Propylene Glycol, Serine, Sodium Hyaluronate, Sodium Lactate, Sodium PCA, Threonine, Tocopheryl Acetate, Triethanolamine, Tussilago Farfara (Coltsfoot) Leaf Extract, Valine, Vitis Vinifera (Grape) Seed Extract, Phenoxyethanol, Sodium Benzoate, Sodium Metabisulfite|
|R + F Lash Boost||Yes||Isopropyl Cloprostenate||Water/Aqua/Eau, Butylene Glycol, Hydroxyethylcellulose, Keratin, Hydrolyzed Keratin, Biotin, Sodium Hyaluronate, Isopropyl Cloprostenate, Octapeptide-2, Allantoin, Panthenol, Copper Tripeptide-1, Pantethine, Polypeptide-23, Cucurbita Pepo (Pumpkin) Seed Extract, Glycerin, Sea Water, Malus Domestica Fruit Cell Culture Extract, Hydrolyzed Glycosaminoglycans, Prunus Amygdalus Dulcis (Sweet Almond) Fruit Extract, Backhousia Citriodora Leaf Oil, Dipotassium Glycyrrhizate, Rhizobian Gum, Styrene/Acrylates/Ammonium Methacrylate Copolymer, Xanthan Gum, PVP, Lecithin, PEG-12 Dimethicone, Alcohol Denat, Chlorphenesin, Phenoxyethanol, Sorbic Acid, Sodium Hydroxide|
|RevitaLash||Yes||Dechloro Dihydroxy Difluoro Ethylcloprostenolamide||Aqua/Water/Eau, Glycerin, Biotin, Cellulose Gum, Phenoxyethanol, Chlorphenesin, Disodium Phosphate, Phosphoric Acid, Dechloro Dihydroxy Difluoro Ethylcloprostenolamide, Butylene Glycol, Calendula Officinalis Extract, Panax Ginseng Extract, Serenoa Serrulata Extract, Camellia Sinensis Extract, Swertia Japonica Extract, Triticum Vulgare Germ Protein, Pentylene Glycol, Biotinoyl Tripeptide-1, Octapeptide-2|
|neuLASH||Yes||Isopropyl Cloprostenate||Water (Aqua), Butylene Glycol, Hydroxyethylcellulose, Rhizobian Gum, Sodium Hyaluronate, Biotin, Panthenol, Pantethine, Allantoin, Cucurbita Pepo (Pumpkin) Seed Extract, Dipotassium Glycyrrhizate, Sea Water (Maris Aqua), Octapeptide-2, Copper Tripeptide-1, sh-Polypeptide-1, Glycine Soja (Soybean) Oil, Glycerin, Hydrogenated Lecithin, Alcohol, Isopropyl Cloprostenate, Phenoxyethanol, Chlorphenesin, Sorbic Acid, Sodium Hydroxide, Potassium Sorbate, Citric Acid, Disodium EDTA, Sodium Oleate, Dicalcium Phosphate|
|RapidLash||Yes||Isopropyl Cloprostenate||Water (Aqua), Butylene Glycol, HydroxyethylcelIulose, Octapeptide-2, Copper Tripeptide-1, Biotin, Panthenol, sh-Polypeptide-1, Glycine Soja (Soybean) Oil, Cucurbita Pepo (Pumpkin) Seed Extract Sodium Hyaluronate, Hydrolyzed, Glycosaminoglycans, Allantoin, Dipotassium Glycyrrhizate, Pantethine, Hydrogenated Lecithin, Sea Water (Maris Aqua), Glycerin, Rhizobian Gum, Disodium Phosphate, Polysorbate 60, Sodium Phosphate, Ethyl Acetate, Sodium Oleate, Sodium Hydroxide, Citric Acid, Alcohol Denat., lsopropyl Cloprostenate, Phenoxyethanol, Chlorphenesin, Sorbic Acid, Potassium, Sorbate, Disodium EDTA|
|Babe Lash||Yes||Isopropyl Cloprostenate||Aqua (Water), Glycerin, Panthenol, Sodium Citrate, Leuconostoc / Radish Root Ferment Filtrate, Alanine, Alcohol, Arbutin, Arginine, Aspartic Acid, Biotin, Calcium Gluconate, Caprylyl|
Glycol, Chamomilla Recutita (Matricaria) Flower Extract, Ethylhexylglycerin, Gluconolactone, Glycine, Hexylene Glycol, Histidine, Hydrolyzed Glycosaminoglycans, Hydroxyethylcellulose,
Isoleucine, Sodium Lactate, Magnesium Ascorbyl Phosphate, Panax Ginseng Root Extract, PCA, Valine, Phenylalanine, Polydextrose, Polysorbate 20, Proline, Propylene Glycol, Serine,
Vitis Vinifera (Grape) Seed Extract, Sodium Hyaluronate, Isopropyl Cloprostenate, Yeast Extract, Sodium PCA, Threonine, Tocopheryl Acetate, Triethanolamine, Phenoxyethanol, Sodium Benzoate, Sodium Metabisulfite.
|Uklash Serum||Yes||Isopropyl Cloprostenate||Aqua, Glycerin, Butylene Glycol, Propanediol, 1,2-Hexanediol, Biotinoyl Tripeptide-1, Camellia Sinensis Leaf Extract, Caprylyl Glycol, Centella Asiatica Extract, Chamomilla Recutita Flower Extract, Ethylhexylglycerin, Glycyrrhiza Glabra Root Extract, Isopropyl Cloprostenate, Myristoyl Pentapeptide-17, Panthenol, Polygonum Cuspidatum Root Extract, Rosmarinus Officinalis Leaf Extract, Scutellaria Baicalensis Root Extract, Tocopherol, Xanthan Gum, Benzoic Acid, Phenoxyethanol, Sodium Benzoate|
Bimatoprost is not the only prostaglandin analog you can find! When analyzing the ingredient list, you can find synthetic prostaglandin compounds such as:
- Isopropyl cloprostenate
- Isopropyl phenyl hydroxypentane
- Dihydroxy cyclopentyl heptane
- Dechloro dihydroxy difluoro ethylcloprostenolamide
So it’s important to be aware of these other names when reading the label.
Lash Serums Without Prostaglandins
- LASHFOOD Serum
- Adoreeye lash serum
- Lash Luxury
- Vegamour GRO lash serum
- The Ordinary lash serum
- Forever Lash
- Velour Lash Serum
- ForLash Serum
Most of these serums are peptides-based which means they stimulate the growth of your own lashes by promoting the production of keratin. Most of these serums will support your eyelashes during the 3 phases of the growth cycle:
- Anagen (active growth phase)
- Catagen (transition phase)
- Telogen (resting phase)
Yes, they have fewer clinical studies to back them up. However, they are much less likely to cause side effects. At the end of the day, you have to make the decision and accept the risks that come with it.
Pro Tip: if you want to know which lash serum I’m currently using (and those that I avoid), check out my best eyelash serums guide here.
What Are Prostaglandins in Lash Serums?
Prostaglandins used in eyelash growth serums increase the length of the eyelashes by extending the anagen (growth phase) of the hair follicle growth cycle.
Are There Prostaglandins in Lash Boost?
Yes. Lash boost contains isopropyl cloprostenate, a synthetic prostaglandin analog.
Does Revitalash Contain Prostaglandins?
Yes. Revitalash contains dechloro dihydroxy difluoro ethylcloprostenolamide, a synthetic prostaglandin analog.
Does Latisse Contain Prostaglandins?
Yes. Latisse contains bimatoprost, a type of prostaglandin.
Do All Lash Serums Contain Prostaglandins?
No. Some lash serums are prostaglandin-free. Most of them use peptides which are chains of amino acids, the building blocks of the proteins found in your eyelashes.
Choosing the right eyelash growth serum is not an easy task.
The problem is that most of them contain synthetic prostaglandins which can cause serious side effects BUT they haven’t gone through the same safety testing as a medication would.
I don’t want to seem pessimistic. You might not experience any adverse events with a prostaglandin serum.
I myself have used one for years. But at least, I knew what I was getting into and made that decision with all the information at my fingertips.
I hope this list helps you in your decision. Of course, it is not exhaustive and there might be other lash serums not mentioned here. If you want me to take a look at a particular serum, just drop me a comment below!